In the journal AIDS, David Goldstein and colleagues at CHAVI report that a SNP earlier found to correlate with a lower HIV-1 viral set point does not restrict growth of the virus in cell culture.
In Neurobiology of Aging, Ornit Chiba-Falek and Jeanette McCarthy report evidence to suggest that genetic regulation of SORL1 expression plays a role in Alzheimer's disease risk.
In Molecular Biology and Evolution, Jonathan Shaw and colleagues including Greg Wray report the results of a study that is "the first [to] attempt to describe generation-biased gene expression in a plant with a well-developed sporophyte and gametophyte generation."
In PLoS One, Jun Zhu, Kristin Scott and colleagues present evidence that antisense transcription has profound impacts on global gene regulation in S. pombe.
In Genetic Testing and Molecular Biomarkers, Susanne Haga and colleagues say that the "substantial number of researchers who did not consider returning research results suggests that researchers and IRBs need to devote more attention to a topic about which participants are interested in."
In PLoS Computational Biology, Uwe Ohler and William Majoros describe a new and flexible framework for modeling binding site evolution in multiple related genomes, based on phylogenetic pair hidden Markov models that explicitly model the gain and loss of binding sites along a phylogeny.
Uwe Ohler is a collaborator on a paper in Nature that presents evidence that natural selection acts to conserve patterns of gene expression during mid-embryogenesis, providing genome-wide insight into the molecular basis of the hourglass pattern of developmental evolution. The work was featured in a Nature News & Views and by Discovery News and USA Today.
In BMC Genomics, Lauren Williams and Jennifer Wernegreen reports that a bacterial mutualist of the ant Camponotus vafer is missing glutamine synthetase, a component of the nitrogen recycling pathway.
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