Mohamed A. F. Noor, PhD
Earl D. McLean Professor and Associate Chair of Department of Biology
One of the greatest unsolved questions in biology is how continuous processes of evolutionary change produce the discontinuous groups known as species. My research has focused on understanding the processes that cause the evolution of barriers to gene exchange between diverging species, particularly hybrid sterility and species mating discrimination. My approaches are primarily classical or molecular genetic using Drosophila species as model organisms. Using these approaches, we have dissected the genetic basis of these barriers to gene exchange using molecular markers and QTL mapping methodologies or gene expression approaches. The recent availability of multiple whole-genome sequences (both publicly and those we have obtained ourselves) has dramatically enhanced the scope of progress we can make. In addition to questions in speciation, we have also been studying the effects of fine-scale recombination heterogeneity on various evolutionary parameters including nucleotide diversity, divergence, and codon bias. See my lab web page for more information.
Learn more about Dr. Noor's research in GenomeLIFE
Recent Publications
Heil CS, Noor MA,
Genetics. 2013 Jun;194(2):335-9. Abstract
McGaugh SE, Heil CS, Manzano-Winkler B, Loewe L, Goldstein S, Himmel TL, Noor MA,
PLoS Biol. 2012 Nov;10(11):e1001422. Abstract
Hoehn KB, McGaugh SE, Noor MA,
J Mol Evol. 2012 Nov 7;. Abstract
Heil CS, Noor MA,
PLoS One. 2012;7(9):e45055. Abstract
McDermott SR, Noor MA,
J Evol Biol. 2012 Oct;25(10):2023-32. Abstract