The Gersbach Lab is focused on engineering new methods for directing cell behavior to regenerate diseased or damaged tissues and treat genetic diseases. We are particularly interested in developing and applying technologies that manipulate cellular processes at the genetic level. Our work capitalizes on the products of the Genomic Revolution and modern advances in the fields of genetic reprogramming, gene delivery, protein engineering, stem cell transplantation, and synthetic biology to create innovative biologic approaches to improving human health. These studies also facilitate a better understanding of complex processes including organogenesis, cell lineage determination, and gene regulation that will ultimately lead to improved design of drugs and biotherapeutics. Our efforts are catalyzed by interdisciplinary collaborations with investigators in engineering and medicine at Duke and other institutions.
Learn more about Dr. Gersbach's research in GenomeLIFE
Ousterout DG, Perez-Pinera P, Thakore PI, Kabadi AM, Brown MT, Qin X, Fedrigo O, Mouly V, Tremblay JP, Gersbach CA, Mol Ther. 2013 Jun 4;. Abstract
Dumbauld DW, Lee TT, Singh A, Scrimgeour J, Gersbach CA, Zamir EA, Fu J, Chen CS, Curtis JE, Craig SW, García AJ, Proc Natl Acad Sci U S A. 2013 May 28;. Abstract
Gaj T, Gersbach CA, Barbas CF, Trends Biotechnol. 2013 May 8;. Abstract
Gibson TM, Gersbach CA, Biotechnol J. 2013 Apr;8(4):397-407. Abstract
Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA, Nat Methods. 2013 Mar;10(3):239-42. Abstract
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